UTILIZATION OF BINAHONG (ANREDERA CORDIFOLIA (TEN.) STEENIS) LEAVES EXTRACT AS HERBAL MEDICINE VIA ULTRASONICATION

Dennis Farina Nury, Muhammad Zulfikar Luthfi

Sari


The leaves of Anredera cordifolia, or binahong, are one of the herbal plants with a high potential for antioxidants and have been reported to be rich in flavonoids. This study aimed to determine the best operating conditions in the ultrasonication extraction method from binahong leaves extract on the yield obtained. Experiments were conducted into how extraction conditions affected the ultrasonication extraction of binahong leaves. Different extraction parameters, such as ethanol concentration (20–100%), time (10–40 min), temperature (30–70 C), and yield impacts, were used to extract powdered dried binahong leaves. The results showed all extraction parameters to have significant effects on yield obtained. The maximum yield of extract from binahong leaves was obtained at 60 ml of ethanol concentration, 20 minutes of extraction time, and 50°C ultrasonication bath temperature. Thus, it can be concluded that the ultrasonication process is a good way to obtain a better yield of simplicia of binahong leaves extract as a therapeutic herbal in the future.

Kata Kunci


Antioxidant; binahong leaves; therapeutic; ultrasonication; simplicia

Teks Lengkap:

PDF (English)

Referensi


A. S. Wanjari and D. S. Wanjari, “An Overview on Herbal Medicine,” Res. J. Pharmacogn. Phytochem., vol. 11, no. 1, p. 14, 2019, doi: 10.5958/0975-4385.2019.00003.7.

N. Tran, B. Pham, and L. Le, “Bioactive compounds in anti-diabetic plants: From herbal medicine to modern drug discovery,” Biology (Basel)., vol. 9, no. 9, pp. 1–31, 2020, doi: 10.3390/biology9090252.

Dzobo K, “The role of natural products as sources of therapeutic agents for innovative drug discovery,” Compr. Pharmacol., vol. 7, no. 9, pp. 408–422, 2022, [Online]. Available: https://www.sciencedirect.com/referencework/9780128208762/comprehensive-pharmacology

H. Yuan, Q. Ma, L. Ye, and G. Piao, “The traditional medicine and modern medicine from natural products,” Molecules, vol. 21, no. 5, 2016, doi: 10.3390/molecules21050559.

D. F. Nury, T. Widjaja, and F. Kurniawan, “The Effect of Binahong (Anredera cordifolia (Ten.) Steenis) Medicinal Plant Extract Addition on Glucose Detection,” J. Sains dan Seni ITS, vol. 8, no. 2, 2019, doi: 10.12962/j23373520.v8i2.49944.

F. Tedjakusuma and D. Lo, “Functional properties of Anredera cordifolia (Ten.) Steenis: A review,” IOP Conf. Ser. Earth Environ. Sci., vol. 998, no. 1, 2022, doi: 10.1088/1755-1315/998/1/012051.

Dwitiyanti, Y. Harahap, B. Elya, and A. Bahtiar, “Impact of solvent on the characteristics of standardized binahong leaf (Anredera cordifolia (Ten.) Steenis),” Pharmacogn. J., vol. 11, no. 6, pp. 1463–1470, 2019, doi: 10.5530/PJ.2019.11.226.

Himawan HC, Isa AF, and Wiharja DS, “Antioxidant activity of 70% ethanol extract combination of kemangi leaf (Ocimum Americanum Linn) and binahong Leaf (Anredera cordifolia (Ten.) Steenis) using DPPH.,” J. Phys. Conf. Ser. , vol. 1764, pp. 1–7, 2021, [Online]. Available: https://iopscience.iop.org/article/10.1088/1742-6596/1764/1/012009/pdf

N. F. Utami, U. Suhendar, and A. H. Amini, “Utilization of Binahong (Anredera cordifolia) Leaves Extract from Bogor Regency as Free Radical Scavenging Activity,” J. Sains Nat., vol. 12, no. 1, p. 36, 2022, doi: 10.31938/jsn.v12i1.327.

N. A. A. R. Zahari, G. H. Chong, L. C. Abdullah, and B. L. Chua, “Ultrasonic-assisted extraction (UAE) process on thymol concentration from Plectranthus amboinicus leaves: Kinetic modeling and optimization,” Processes, vol. 8, no. 3, 2020, doi: 10.3390/pr8030322.

M. M. Hasan, T. Bashir, and H. Bae, “Use of ultrasonication technology for the increased production of plant secondary metabolites,” Molecules, 2017, [Online]. Available: https://www.mdpi.com/1420-3049/22/7/1046%0Ahttps://www.mdpi.com/1420-3049/22/7/1046/pdf

C. O. Perera and M. A. J. Alzahrani, “Ultrasound as a pre-treatment for extraction of bioactive compounds and food safety: A review,” Lwt, vol. 142, 2021, doi: 10.1016/j.lwt.2021.111114.

N. A. Al-Dhabi, K. Ponmurugan, and P. Maran Jeganathan, “Development and validation of ultrasound-assisted solid-liquid extraction of phenolic compounds from waste spent coffee grounds,” Ultrason. Sonochem., vol. 34, pp. 206–213, 2017, doi: 10.1016/j.ultsonch.2016.05.005.

N. P. E. Hikmawanti, S. Fatmawati, and A. W. Asri, “The effect of ethanol concentrations as the extraction solvent on antioxidant activity of Katuk (Sauropus androgynus (L.) Merr.) leaves extracts,” IOP Conf. Ser. Earth Environ. Sci., vol. 755, no. 1, 2021, doi: 10.1088/1755-1315/755/1/012060.

M. Oroian, F. Ursachi, and F. Dranca, “Influence of ultrasonic amplitude, temperature, time and solvent concentration on bioactive compounds extraction from propolis,” Ultrason. Sonochem., vol. 64, 2020, doi: 10.1016/j.ultsonch.2020.105021.

N. Y. Chesnokova, L. V. Levochkina, Y. V. Prikhod’Ko, A. A. Kuznetsova, and P. A. Chebukin, “Influence of ultrasound and extraction conditions on the intensity of extraction of anthocyanin pigment from berry raw materials,” IOP Conf. Ser. Earth Environ. Sci., vol. 848, no. 1, 2021, doi: 10.1088/1755-1315/848/1/012211.




DOI: http://dx.doi.org/10.56444/cjce.v5i1.4764

Article Metrics

Sari view : 28 times
PDF (English) - 0 times

Refbacks

  • Saat ini tidak ada refbacks.